Follow the Hib 4-dose series tables (above) unless one of the following exceptions applies:

Exception 1:If a child is >= 7 months and < 12 months at time of execution and
- A. Has received 0 doses prior to 7 months then:
  - 3 doses are indicated (dose 2, 3, and 4) at => 7 months.
  - Routine age is 7 months for target dose 2.
  - Recommended interval is 28 days between doses 2 and 3; recommended interval is 56 days between doses 3 and 4.
  - For dose 4, absolute minimum age is 1 year - 4 days and recommended age is 12 months.
    - If target dose 4 is administered at < 1 year - 4 days the shot is Invalid and the reason code is BELOW_MINIMUM_AGE_FINAL_DOSE.

- Or -

- B. Has received 1 dose prior to 7 months and 1 dose at <= 28 days prior to 12 months then:
  - 3 doses are indicated (doses 1, 3, 4 or doses 2, 3, 4).
  - Recommended interval is 56 days between the final 2 doses.

Exception 2: If a child is >= 12 months and < 15 months at time of execution and
- A. Has received < 2 doses administered at < 12 months of age then:
  - 2 doses are indicated (dose 3 and 4) at >= 12 months.
  - Routine age is 12 months for target dose 3.
  - Recommended interval is 28 days between doses 2 and 3; recommended interval is 56 days between doses 3 and 4.

- Or -

- B. Has received 2 doses administered at < 12 months of age then:
  - 1 dose is indicated (dose 4) at >= 12 months.
  - Routine age is 12 months for target dose 4.
  - Recommended interval is 56 days between doses 3 and 4.

Exception 3: If a child is >= 15 months and < 5 years at time of execution and has not completed the series prior to the age of 15 months then:
- 1 dose is indicated (dose 4) at >= 15 months.
- Routine age is 15 months for target dose 4.
- Recommended interval is 56 days between doses 3 and 4.

The Hib component of CVX 50 (which is CVX 48) is evaluated as Valid only when it is the final dose of the series, follows a previous dose of Hib, and patient is => 1 year - 4 days; otherwise, the Hib component of CVX 50 (which is CVX 48) is Invalid and the reason code is BOOSTER_ONLY).¹
This rule applies only to CVX 48 when it is the Hib component of the combination vaccine CVX 50; this rule does not apply when CVX 48 is given by itself or as part of any other combination vaccine.

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