HPV Vaccine Group
HPV Vaccine Group Evaluation and Forecasting Rules
General Rules for HPV
General rules are not series-specific; general rules apply to the entire vaccine group.
Rules Based on Patient's Age
For males and females:
- If a patient is < 27 years old, follow the Immunization Series and Selection Rules (listed below).
- If a patient is >= 27 years and < 46 years old and:
- Has one or more doses at < 46 years old, has not completed the series, and will be < 46 years old at the next recommended due date, then recommend based on table rules.
- Does NOT have any doses at < 46 years old, then Recommendation is Conditional and the reason code is CLINICAL_PATIENT_DISCRETION.
- Shots administered to a patient who is >= 27 years and < 46 years will continue to be evaluated (based on minimum intervals) and, if valid, will count toward completion of the series.
- If the patient is >= 46 years old, (or will be >= 46 years old at the next recommended due date), then:
- Recommendation is Not Recommended and the reason code is TOO_OLD.
- If a dose is administered at >= 46 years, the Evaluation is Accepted and the reason code is ABOVE_REC_AGE_SERIES.
- The series can NOT be initiated and completed once the patient is >= 46 years old.
Rules for Recommending at the CVX Code vs. Vaccine Group Level
When recommending in the HPV 3-dose series or HPV 2-dose series, always recommend at the vaccine group level.
HPV Vaccines
CVX Code | Name |
---|---|
62 | HPV, quadrivalent (Gardasil) |
118 | HPV, bivalent (Cervarix) |
137 | HPV, unspecified formulation |
165 | HPV9 |
CVX Code Specific Rules
Rule for CVX 118 (HPV, bivalent (Cervarix)
- CVX 118 is not licensed for use in males. If CVX 118 (HPV, bivalent (Cervarix) is reported for a male patient, then evaluate as Accepted and the reason code is VACCINE_NOT_LICENSED_FOR_MALES. Ignore the reported CVX 118 when determining the recommended vaccine and calculating the recommended due date for the next target dose.
Combination Vaccines that Include HPV
No combination vaccines exist, at this time, that include HPV.
Immunization Series and Selection Rules
Series Name
- HPV 2-dose Series
- HPV 3-dose Series
Series Selection Rules
The HPV 2-dose series applies if any one of the following is true:
- If the patient < 15 years old and no doses have been administered
- If dose 1 was administered and is given to a patient >= 9 years - 4 days old and < 15 years old
- If dose 1 was administered and is given to a patient >= 9 years - 4 days old and < 15 years old and
- target dose 2 is valid for the HPV 2-dose series, the HPV 2-dose series applies.
- target dose 2 is invalid or accepted for the HPV 2-dose series, but valid for HPV 3-dose series, the HPV 3-dose series applies. (Note: Once the 3-dose series is triggered, it cannot switch back to applying the 2-dose series.)
- target dose 2 is invalid or accepted for BOTH the HPV 2-dose series and HPV 3-dose series, the HPV 2-dose series applies.
Otherwise, the HPV 3-dose series applies.
Immunization Series: HPV 2-dose Series
The HPV 2-dose series is complete after 2 doses.
Vaccine Dose Parameters - Minimum and Routine Ages
Dose | Series Name | Absolute Minimum | Minimum Age | Routine | Latest Recommended Age (less than) | Valid CVX Code(s) per Dose for this Series | Invalid CVX Code(s) per Dose for this Series |
---|---|---|---|---|---|---|---|
1 | HPV 2-dose | 9 years - 4 days | 9 years | 11 years | 13 years + 4 weeks | 62, 118, 137, 165 | N/A |
2 | HPV 2-dose | N/A | N/A | N/A | N/A | 62, 118, 137, 165 | N/A |
Vaccine Dose Parameters - Minimum and Recommended Intervals
Doses | Series Name | Absolute Minimum Interval | Minimum Interval | Recommended Interval | Latest Recommended Interval (less than) |
---|---|---|---|---|---|
Dose 1 to 2 | HPV 2-dose | 5 months - 4 days | 5 months | 6 months | 13 months + 4 weeks |
Series Special Rules
- There are no special rules for this series.
Immunization Series: HPV 3-dose Series
The HPV 3-dose series is complete after 3 doses.
Vaccine Dose Parameters - Minimum and Routine Ages
Dose | Series Name | Absolute Minimum | Minimum Age | Routine | Latest Recommended Age (less than) | Valid CVX Code(s) per Dose for this Series | Invalid CVX Code(s) per Dose for this Series |
---|---|---|---|---|---|---|---|
1 | HPV 3-dose | 9 years - 4 days | 9 years | 11 years | If Patient age < 15 years: 13 years + 4 weeks If Patient age >= 15 years: 15 years | 62, 118, 137, 165 | N/A |
2 | HPV 3-dose | N/A | N/A | N/A | N/A | 62, 118, 137, 165 | N/A |
3 | HPV 3-dose | N/A | N/A | N/A | N/A | 62, 118, 137, 165 | N/A |
Vaccine Dose Parameters - Minimum and Recommended Intervals
Doses | Series Name | Absolute Minimum Interval | Minimum Interval | Recommended Interval | Latest Recommended Interval (less than) |
---|---|---|---|---|---|
Dose 1 to 2 | HPV 3-dose | 24 days | 28 days | 4 weeks | If Dose 1 administered at age < 15 years: 13 months + 4 weeks If Dose 1 administered at age >= 15 years: 16 weeks |
Dose 2 to 3 | HPV 3-dose | 80 days | 84 days | 4 months | N/A |
Dose 1 to 3 | HPV 3-dose | 5 months - 4 days | 168 days | 6 months | If Dose 1 administered at age < 15 years: 13 months + 4 weeks If Dose 1 administered at age >= 15 years: 7 months + 4 weeks |
Series Special Rules
- There are no special rules for this series.