Hep A Vaccine Group

Hep A Vaccine Group

Table of Contents

Hep A Vaccine Group Evaluation and Forecasting Rules

General Rules for Hep A

General rules are not series-specific; general rules apply to the entire vaccine group.

Rules Based on Patient's Age

  • If a patient is >= 19 years of age and did NOT receive a shot of Hep A, then the Recommendation is Conditional and the reason code is HIGH_RISK.
  • Shots administered to a patient who is >= 19 years of age will continue to be evaluated and, if valid, will count toward completion of the series.

Proof of Immunity Rules

  • If a patient has immunity (reported as having a positive titer or serology) vaccine is not recommended; Recommendation is Not Recommended and the reason code is PROOF_OF_IMMUNITY.
  • Any shot administered prior to the date of immunity is evaluated as Valid or Invalid, based on minimum age and minimum interval rules.
  • Any shot administered on or after the date of immunity is evaluated as Accepted with a reason code of PROOF_OF_IMMUNITY unless the series is COMPLETE.

Hep A Vaccines

CVX Code

Name

Absolute Minimum AgeAbsolute Maximum Age
83Hep A, ped/adol, 2 dose12 months - 4 days19 years - 1 day
84Hep A, ped/adol, 3 dose12 months - 4 days19 years - 1 day

31

Hep A, pediatric, unspecified formulation 12 months - 4 days19 years - 1 day
52Hep A, adult12 months - 4 daysN/A
85Hep A, unspecified formulation12 months - 4 daysN/A

Combination Vaccines that Include Hep A 

CVX Code

Vaccine Name

Component
CVX Code

Component
Vaccine Name

104

Hep A-Hep B (Twinrix)

83

Hep A peds/adol, 2 dose


CVX Code Specific Rules

CVX Code Absolute Maximum Age

  • If one of the CVX codes in the table above is administered above the absolute maximum age for that CVX code, then the Evaluation is Invalid and the reason code is ABOVE_MAXIMUM_AGE_VACCINE, per the ICE General Rule "Evaluation of Shots Above the Vaccine Code Absolute Maximum Age."

    • There is no interval required between the Invalid shot and the next target dose. 

Immunization Series and Selection Rules

Series Name

  • Hep A 2-dose Series
  • Hep A 3-dose Series1,2

Series Selection Rules

The Hep A 3-dose series applies only if the following is true:

  1. CVX 104 (Twinrix) is given to a patient >= 18 years - 4 days old as dose 1 and/or dose 2.1
  2. If the 3-dose series is selected via the above condition but the 2-dose series completed before the 3-dose series, change the selection to the 2-dose complete series. Furthermore, for each previously Invalid shot in the 2-dose series that was marked Valid in the 3-dose series, change the evaluation for the shot to Accepted / VACCINE_NOT_COUNTED_BASED_ON_MOST_RECENT_VACCINE_GIVEN.

Otherwise, the Hep A 2-dose series applies.

Notes

  • 1The Hep A adult 3-dose series is used to accommodate Twinrix administered to patients > = 18 years - 4 days of age.
  • 2There is a 4-dose Twinrix series (as well as a 4-dose Hep B series) that is an accepted, accelerated schedule (used often at treatment facilities). This is currently not supported by ICE.

Immunization Series: Hep A 2-dose Series

Vaccine Dose Parameters - Minimum and Routine Ages

Dose

Series Name

Absolute Minimum
 Age

Minimum Age

Routine
Age 

Latest Recommended Age

(less than)

Valid CVX Code(s) per Dose for this SeriesInvalid CVX Code(s) per Dose for this Series

1

Hep A 2-dose Series

12 months - 4 days

12 months

12 months

24 months + 4 weeks83, 84, 31, 52, 85, 104N/A
2 Hep A 2-dose Series
18 months - 4 days18 months
18 months24 months + 4 weeks 83, 84, 31, 52, 85, 104N/A

Vaccine Dose Parameters - Minimum and Recommended Intervals

Doses

Series Name

Absolute Minimum Interval

Minimum Interval

Recommended Interval

Latest Recommended Interval

(less than)

Dose 1 to 2

Hep A 2-dose Series

6 months - 4 days

6 months
6 months19 months + 4 weeks

Series Special Rules 

  • Target dose 2 will be evaluated as valid if administered >= 6 months - 4 days from dose 1, even if there have been invalid shots administered. 
    • Example: If dose 1 is administered at 1 year, invalid shot 2 is administered at 1 year 5 months, and target dose 2 is administered at 1 year 6 months, then target dose 2 is evaluated as valid and counts as dose 2, completing the 2-dose series.
  • If CVX 104 is administered for target dose 2 at >= 18 years - 4 days of age, then switch this series to the Hep A 3-dose Series starting with target dose 2.

Immunization Series: Hep A 3-dose Series

Vaccine Dose Parameters - Minimum and Routine Ages 

Dose

Series Name

 Absolute Minimum
Age

Minimum Age

Routine
Age

Latest Recommended Age

(less than)

Valid CVX Code(s) per Dose for this SeriesInvalid CVX Code(s) per Dose for this Series

1

Hep A 3-dose Series

18 years - 4 days

19 years

19 years

N/A83, 84, 31, 52, 85, 104N/A

2

Hep A 3-dose Series

N/A

N/A

N/A

N/A83, 84, 31, 52, 85, 104N/A

3

Hep A 3-dose Series

N/A

N/A

N/A

N/A83, 84, 31, 52, 85, 104N/A

 Vaccine Dose Parameters - Minimum and Recommended Intervals

Doses

Series Name

Absolute Minimum Interval

Minimum Interval

Recommended Interval

Latest Recommended Interval

(less than)

Dose 1 to 2

Hep A 3-dose Series

24 days

28 days

28 days

N/A

Dose 2 to 3

Hep A 3-dose Series

5 months - 4 days

5 months

5 months

N/A

Series Special Rules 

  • If CVX 104 is administered at >= 18 years - 4 days, there is no maximum age for the Hep A vaccine component (CVX 83).
  • If dose 1 and dose 2 are administered at < 19 years and the interval between dose 1 and dose 2 is >= 6 months - 4 days, the series is complete.