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Rules Based on Patient's Age
- If a patient is >= 19 years old and did NOT get a shot of Hep B, then the Recommendation is Conditional and the reason code is HIGH_RISK.
- Shots administered to a patient who is >= 19 years of age will continue to be evaluated and, if valid, will count toward completion of the series.
Proof of Immunity Rules- If a patient has immunity (reported as having a positive titer or serology) vaccine is not recommended.
- Any shot administered prior to the date of immunity is evaluated as Valid or Invalid, based on minimum age and minimum interval rules.
- Any shot administered on or after the date of immunity is evaluated as Accepted with a reason code of PROOF_OF_IMMUNITY; Recommendation is Not Recommended and the reason code is PROOF_OF_IMMUNITY.
Atkinson (Enough is Enough) Rule
- If a patient receives target dose 3 that is invalid (e.g. due to minimum interval violation or minimum age violation), there is no minimum interval between the next-to-last shot (invalid shot) and dose 3 (the final dose), but the patient must a.) meet the minimum interval between dose 2 and the final dose (52 days), b.) meet the minimum age for the final dose in the series (164 days), and c.) meet the minimum interval between dose 1 and dose 3 of 16 weeks.
- Example: Dose 1 at 28 days, dose 2 at 113 days, invalid shot 3 (target dose 3) at 163 days (below minimum age for the series and below minimum interval), shot 4/dose 3 at 165 days = series complete (even though there is only a 2-day interval between shot 3 and shot 4/dose 3), based on the Atkinson Rule.
- The Atkinson rule does not apply to recommendations; when determining the date due the recommended interval is calculated from the last shot given.
Select Adjuvant Product IntervalRules for Recommending at the CVX Code vs. Vaccine Group Level- When recommending in the Hep B 3-dose Newborn Series or Hep B 3-dose Child/Adult Series, always recommend at the vaccine group level.
- When recommending in the Hep B 2-dose Adult Series, always recommend at the CVX level; vaccine recommended should be CVX 189 (Hep B, adjuvanted).
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CVX Code | Name | Absolute Minimum Age | Absolute Maximum Age |
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08 | Hep B, adolescent or pediatric |
| 20 years - 1 day |
42 | Hep B, adolescent/high risk infant |
| 20 years - 1 day |
43 | Hep B, adult |
| N/A |
44 | Hep B, dialysis |
| N/A |
45 | Hep B, unspecified formulation |
| N/A |
189 | Hep B, adjuvanted | 18 years - 4 days | N/A |
220 | Hep B recombinant, 3-antigen, Al(OH)3 | 18 years - days | N/A |
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CVX Code Specific RulesCVX Code Maximum Age
- CVX 08 (Hep B, adolescent or pediatric) and CVX 42 (Hep B, adolescent/high risk infant) will be evaluated as follows:
- Invalid/ INSUFFICIENT_ANTIGEN if administered to a patient who is >= 20 years old.
- Valid (as long as minimum interval/minimum age requirements are met, where applicable) if administered to a patient who is < 20 years old.
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Dose | Series Name | Absolute Minimum Age | Minimum Age | Routine Age | Latest Recommended Age (less than) | Valid CVX Code(s) per Dose for this Series | Invalid CVX Code(s) per Dose for this Series |
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1 | Hep B Newborn | 0 days | 0 days | 0 days | 4 weeks | 08, 42, 45, 43, 44, 51, 110, 104, 102, 132, 146, 189, 220
| N/A |
2 | Hep B Newborn | 24 days | 28 days | 1 month1 | 3 months + 4 weeks | 08, 42, 45, 43, 44, 51, 110, 104, 102, 132, 146, 189, 220
| N/A |
3 | Hep B Newborn | 164 days | 168 days | 6 months | 19 months + 4 weeks | 08, 42, 45, 43, 44, 51, 110, 104, 102, 132, 146, 189, 220
| N/A |
Vaccine Dose Parameters - Minimum and Recommended Intervals
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Dose | Series Name | Absolute Minimum Age | Minimum Age | Routine Age | Latest Recommended Age (less than) | Valid CVX Code(s) per Dose for this Series | Invalid CVX Code(s) per Dose for this Series |
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1 | Hep B Child/Adult | 28 days1 | 28 days | 2 months | 3 months + 4 weeks | 08, 42, 45, 43, 44, 51, 110, 104, 102, 132, 146, 189, 220
| N/A |
2 | Hep B Child/Adult | 52 days | 56 days | 4 months | 5 months + 4 weeks | 08, 42, 45, 43, 44, 51, 110, 104, 102, 132, 146, 189, 220
| N/A |
3 | Hep B Child/Adult | 164 days | 168 days | 6 months | 19 months + 4 weeks | 08, 42, 45, 43, 44, 51, 110, 104, 102, 132, 146, 189, 220
| N/A |
Vaccine Dose Parameters - Minimum and Recommended Intervals
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