Table of Contents

Varicella Vaccine Group Evaluation and Forecasting Rules

General Rules for Varicella

General rules are not series-specific; general rules apply to the entire vaccine group.

For persons born prior to 1/1/1980, if the series is NOT complete, Recommendation is Conditional and the reason code is HIGH_RISK.

If a patient has immunity (reported as having a positive titer or serology) vaccine is not recommended.
Any shot administered prior to the date of immunity is evaluated as Valid or Invalid, based on minimum age and minimum interval rules.
Any shot administered on or after the date of immunity is evaluated as Accepted with a reason code of PROOF_OF_IMMUNITY; Recommendation is Not Recommended and the reason code is PROOF_OF_IMMUNITY.

If a patient has documented history of varicella (clinician verified) vaccine is not recommended.
Any shot administered prior to the disease history date is evaluated as Valid or Invalid, based on minimum age and minimum interval rules.
Any shot administered on or after the disease history date is evaluated as Accepted with a reason code of PROOF_OF_DISEASE; Recommendation is Not Recommended and the reason code is DISEASE_DOCUMENTED.

The Live Vaccine Interval rule (also referred to as the Live Virus rule) applies to all varicella vaccines. For rule details, see the Live Vaccine Interval rule on the General ICE Rules page.

CVX Code	Name
21	Varicella

CVX Code	Vaccine Name	Component CVX Code	Component Vaccine Name
94	MMRV	21	Varicella

CVX 94 (MMRV) is not licensed for patients >= 13 years old. This does not affect evaluation; however, see the rule Vaccine Administered Outside of Licensed Age Range on the General ICE Rules page.

The Varicella series is complete after 2 doses.

Vaccine Dose Parameters - Minimum and Routine Ages

Dose	Series Name	Absolute Minimum Age	Minimum Age	Routine Age	Latest Recommended Age (less than)	Valid CVX Code(s) per Dose for this Series	Invalid CVX Code(s) per Dose for this Series
1	Varicella	361 days	1 year	1 year	16 months + 4 weeks	21, 94	N/A
2	Varicella	389 days^₁	15 months	4 years	7 years + 4 weeks	21, 94	N/A

Vaccine Dose Parameters - Minimum and Recommended Intervals

Doses	Series Name	Absolute Minimum Interval	Minimum Interval	Minimum Recommended Interval³	Latest Recommended Interval (less than)
Dose 1 to 2	Varicella	28 days²	12 weeks if < 13 years of age 4 weeks if >= 13 years of age	84 days (12 weeks) if < 13 years of age 28 days (4 weeks) if >= 13 years of age	6 years + 4 weeks

Recommended interval between dose 1 and dose 2 is dependent upon the age of the patient at dose 1 (< or >= 13 years)
- If the shot for target dose 1 is invalid, the recommended interval between the invalid shot and dose 1 is 28 days.

The absolute minimum age of 389 days¹ for dose 2 does not include a 4-day grace period.
The minimum interval between dose 1 and dose 2 (28 days)² differs from the CDC CDSi minimum interval of 24 days for patients that receive their dose 2 of varicella at > = 13 years of age. In order to be consistent with the 28-day varicella minimum interval and the 28-day Live Vaccine minimum interval, the ICE Workgroup decided not to apply the 4-day grace period to patients receiving varicella at > = 13 years of age and for live vaccines from the same vaccine group.
This recommended interval³ differs from the CDC CDSi recommended interval of 3 years. While the recommended intervals differ, in practice ICE and CDC CDSi will come up with the same recommended due date. CDC CDSi only uses the recommended interval when the recommended age is not provided. See the CDC CDSi Logic Specification for details on how they calculate their recommended due date.