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For persons born prior to 1/1/1980, if the series is NOT complete, the Recommendation is Conditional and the reason code is HIGH_RISK.

If a patient has immunity (reported as having a positive titer or serology) vaccine is not recommended.
Any shot administered prior to the date of immunity is evaluated as Valid or Invalid, based on minimum age and minimum interval rules.
Any shot administered on or after the date of immunity is evaluated as Accepted with a reason code of PROOF_OF_IMMUNITY; Recommendation is Not Recommended and the reason code is PROOF_OF_IMMUNITY.

If a patient has documented history of varicella (clinician verified) vaccine is not recommended.
Any shot administered prior to the disease history date is evaluated as Valid or Invalid, based on minimum age and minimum interval rules.
Any shot administered on or after the disease history date is evaluated as Accepted with a reason code of DISEASE_DOCUMENTED; Recommendation is Not Recommended and the reason code is DISEASE_DOCUMENTED.

The Live Vaccine Interval rule (also referred to as the Live Virus rule) applies to all varicella vaccines. For rule details, see the Live Vaccine Interval rule on the General ICE Rules page.

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Dose	Series Name	Absolute Minimum Age	Minimum Age	Routine Age	Latest Recommended Age (less than)	Valid CVX Code(s) per Dose for this Series	Invalid CVX Code(s) per Dose for this Series
1	Varicella	1 year - 4 days	1 year	1 year	16 months + 4 weeks	21, 94	N/A
2	Varicella	389 days^₁ 13 months	15 months	4 years	7 years + 4 weeks	21, 94	N/A

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Doses	Series Name	Absolute Minimum Interval	Minimum Interval	Minimum Recommended Interval³	Latest Recommended Interval (less than)
Dose 1 to 2	Varicella28 days²	28 days if < 13 years of age 24 days if >= 13 years of age¹	12 weeks if < 13 years of age 4 weeks if >= 13 years of age	84 days (12 weeks) if < 13 years of age² 28 days (4 weeks) if >= 13 years of age	6 years + 4 weeks

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Recommended interval between dose 1 and dose 2 is dependent upon the age of the patient at dose 1 (< or >= 13 years)
- If the shot for target dose 1 is invalid, the recommended interval between the invalid shot and target dose 1 is 28 days.

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The absolute minimum age of 389 days¹ for dose 2 does not include a 4-day grace period.

The minimum interval between dose 1 and dose 2 (28 days)² differs from the CDC CDSi ¹Per the Live Vaccine Interval rule, an absolute minimum interval of 24 28 days for patients that receive their dose 2 of varicella at > = 13 years of age. In order to be consistent with the 28-day varicella minimum interval and the 28-day Live Vaccine minimum interval, the ICE Workgroup decided not to apply the 4-day grace period to patients receiving varicella at > = 13 years of age and for live vaccines from the same vaccine group. This recommended interval³ is required for CVX 94 (MMRV). For rule details, see the Live Vaccine Interval rule on the General ICE Rules page.
²The recommended interval for < 13 years of age differs from the CDC CDSi recommended interval of 3 years. While the recommended intervals differ, in practice ICE and CDC CDSi will come up with the same recommended due date. CDC CDSi only uses the recommended interval when the recommended age is not provided. See the CDC CDSi Logic Specification for details on how they calculate their recommended due date.

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